MCB112
Biological sequence analysis (Fall 2024)
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Weekly schedule
w00: intro lecture section "pset" "answers"
w01: genomes lecture [molbio] [py] pset answers
w02: probability lecture section pset answers
w03: data lecture section pset answers
w04: alignment lecture section pset answers
w05: Bayes lecture section pset answers
w06: p-values lecture section pset answers
w07: EM lecture section pset answers
w08: HMMs lecture section pset answers
w09: k-means lecture section pset answers
w10: regression lecture section pset answers
w11: PCA lecture section pset answers
w12: work lecture - - -
w13: trees lecture section pset answers
Contents
  • Intuition Around Alignment
  • Implementing Alignment
Sean Eddy   |   Harvard MCB
MCB112
Biological sequence analysis (Fall 2024)
Home   |   Schedule   |   Q&A forum   |   Canvas

Section 04: Alignment

*Exercises by Joshua Park (2024)

Intuition Around Alignment

We will start by building some intuition by filling in a dynamic programming matrix by hand alignment_manual.xlsx. Solutions for the global case (alignment_manual_glo.xlsx) and local case (alignment_manual_loc.xlsx).

Implementing Alignment

We will implement global and local version of the dynamic programming algorithms w04-section-exercises.ipynb. Solutions for exercises: w04-section-solutions.ipynb.